Its tough man..

I came to deduction only by POE.

let us wait for some Gyan from our master's in CR's

Received a PM.

Actually, the right answer is clearly E. In GMATprep, the correct answer is signaled by a small rectangle around the correct choice.
C is the answer that the original poster provided.

E is correct because sleep deprivation can only be used for a limited amount of time - in the end, you will have to sleep or your body will just succumb to the need.

DanaJ,

Yes OA is E. But passage tells that missing sleep increases lift depression level so does it make sense that if someone tell that more side effect of sleep deprivation is there like in choice C.

Pls comments?

I think that feeling like you've had several ounces of alcohol is not as bad as side effects from psychotic medication - sadly, I actually know so, since I have a very close family member that suffers from a mental illness.

The argument goes as follows:
- sleep deprivation --- effective
- pills --- effective, but with severe side effects
- still, pills are used more often than sleep deprivation

This means that there must be something "wrong" with sleep deprivation that outweighs the side effects of drugs. Feeling like you've had a drink is not nearly as bad as some side effects. Besides, if you sleep for just a few minutes, you're right back where you started, which makes this technique ineffective on the long run.

E seems to be the best choice here