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adi_800
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Paragraph starts are indicated by the bold words...
Protein synthesis begins when the gene encoding a protein is activated. The gene's sequence of nucleotides is transcribed into a molecule of messenger RNA (mRNA), which reproduces the information contained in that sequence. Transported outside the nucleus to the cytoplasm, the mRNA is translated into the protein it encodes by an organelle known as a ribosome, which strings together amino acids in the order specified by the sequence of elements in the mRNA molecule. Since the amount of mRNA in a cell determines the amount of the corresponding protein, factors affecting the abundance of mRNA's play a major part in the normal functioning of a cell by appropriately regulating protein synthesis. For example, an excess of certain proteins can cause cells to proliferate abnormally and become cancerous; a lack of the protein insulin results in diabetes.
Biologists once assumed that the variable rates at which cells synthesize different mRNA's determine the quantities of mRNA's and their corresponding proteins in a cell. However, recent investigations have shown that the concentrations of most mRNA's correlate best, not with their synthesis rate, but rather with the equally variable rates at which cells degrade the different mRNA's in their cytoplasm. If a cell degrades both a rapidly and a slowly synthesized mRNA slowly, both mRNA's will accumulate to high levels.
An important example of this phenomenon is the development of red blood cells from their unspecialized parent cells in bone marrow. For red blood cells to accumulate sufficient concentrations of hemoglobin (which transports oxygen) to carry out their main function, the cells' parent cells must simultaneously produce more of the constituent proteins of hemoglobin and less of most other proteins. To do this, the parent cells halt synthesis of non-hemoglobin mRNA's in the nucleus and rapidly degrade copies of the non-hemoglobin mRNA's remaining in the cytoplasm. Halting synthesis of mRNA alone would not affect the quantities of proteins synthesized by the mRNA's still existing in the cytoplasm. Biologists now believe that most cells can regulate protein production most efficiently by varying both mRNA synthesis and degradation, as developing red cells do, rather than by just varying one or the other.
Now, I will first pray for all the members who are gonna give the GMAT that no one gets this kinda passage at first...
I am from Engg back ground and donno anything from Bio side... When i solved this passage, I got 5 right out of 8 n i did not time this passage as i knew im not gonna get the questions right if i don't understand anything....
I dont want to know answers of questions that were asked on this passage... I wanna know how would you all approach this passage..So lets consider a scenario that you are doing a descent job in the overall test...you have passed the first ten qs of the verbal and, on 11th question, up pops this bio passage that you HATE.... Now, what would be your strategy....You start reading the passage and you know you are not getting much after you read two-three sentences....
Then how would you apply the manhattan strategy of taking notes...
the first thing happens is you get demotivated by the language of the passage..then your comprehension goes down..
When the sentence that you this is understandable comes...you start reading with interest and then again passage starts to throw at you sentence that simply mean something in bio terms that you can not understand....
How can make sure that you understand the passage at the best possible level...
This was related to reading the passage... Now down to questions..
You have not understood much n up pops a inference question that you find difficult normally...Also, the q is on technical knowledge that you have not understood n to make the matter even worst...you donno where to make the lookup...you have to search for that text n den read....
Now what would you do...
Is it worth investing time into these questions or you know the chances of u getting this one right are rare n just skip n concentrate on the next SC CR questions...
I am asking this coz this is where your verbal score can take a beating.... If you happen to invest 12-13 minutes on this passage with 4 questions on this passage.....so that means you are on around 15th question and you have spent around 35 minutes...The next task of 26 questions in around 40 minutes can become daunting with 2 RC passage still remaining... N when you are pressed for time in verbal..you tend to lose your comprehension..
Now, this is the point where fellow test takers have gone down...So, I wanna know what is to be done in this scenario...
Btw... I hope you found the passage tough...if you found the passage EASY, then i would rather take a 12th bio book and start studying from that first...
Even if you found this one easy, what would approach be if a tougher passage comes?
Protein synthesis begins when the gene encoding a protein is activated. The gene's sequence of nucleotides is transcribed into a molecule of messenger RNA (mRNA), which reproduces the information contained in that sequence. Transported outside the nucleus to the cytoplasm, the mRNA is translated into the protein it encodes by an organelle known as a ribosome, which strings together amino acids in the order specified by the sequence of elements in the mRNA molecule. Since the amount of mRNA in a cell determines the amount of the corresponding protein, factors affecting the abundance of mRNA's play a major part in the normal functioning of a cell by appropriately regulating protein synthesis. For example, an excess of certain proteins can cause cells to proliferate abnormally and become cancerous; a lack of the protein insulin results in diabetes.
Biologists once assumed that the variable rates at which cells synthesize different mRNA's determine the quantities of mRNA's and their corresponding proteins in a cell. However, recent investigations have shown that the concentrations of most mRNA's correlate best, not with their synthesis rate, but rather with the equally variable rates at which cells degrade the different mRNA's in their cytoplasm. If a cell degrades both a rapidly and a slowly synthesized mRNA slowly, both mRNA's will accumulate to high levels.
An important example of this phenomenon is the development of red blood cells from their unspecialized parent cells in bone marrow. For red blood cells to accumulate sufficient concentrations of hemoglobin (which transports oxygen) to carry out their main function, the cells' parent cells must simultaneously produce more of the constituent proteins of hemoglobin and less of most other proteins. To do this, the parent cells halt synthesis of non-hemoglobin mRNA's in the nucleus and rapidly degrade copies of the non-hemoglobin mRNA's remaining in the cytoplasm. Halting synthesis of mRNA alone would not affect the quantities of proteins synthesized by the mRNA's still existing in the cytoplasm. Biologists now believe that most cells can regulate protein production most efficiently by varying both mRNA synthesis and degradation, as developing red cells do, rather than by just varying one or the other.
Now, I will first pray for all the members who are gonna give the GMAT that no one gets this kinda passage at first...
I am from Engg back ground and donno anything from Bio side... When i solved this passage, I got 5 right out of 8 n i did not time this passage as i knew im not gonna get the questions right if i don't understand anything....
I dont want to know answers of questions that were asked on this passage... I wanna know how would you all approach this passage..So lets consider a scenario that you are doing a descent job in the overall test...you have passed the first ten qs of the verbal and, on 11th question, up pops this bio passage that you HATE.... Now, what would be your strategy....You start reading the passage and you know you are not getting much after you read two-three sentences....
Then how would you apply the manhattan strategy of taking notes...
the first thing happens is you get demotivated by the language of the passage..then your comprehension goes down..
When the sentence that you this is understandable comes...you start reading with interest and then again passage starts to throw at you sentence that simply mean something in bio terms that you can not understand....
How can make sure that you understand the passage at the best possible level...
This was related to reading the passage... Now down to questions..
You have not understood much n up pops a inference question that you find difficult normally...Also, the q is on technical knowledge that you have not understood n to make the matter even worst...you donno where to make the lookup...you have to search for that text n den read....
Now what would you do...
Is it worth investing time into these questions or you know the chances of u getting this one right are rare n just skip n concentrate on the next SC CR questions...
I am asking this coz this is where your verbal score can take a beating.... If you happen to invest 12-13 minutes on this passage with 4 questions on this passage.....so that means you are on around 15th question and you have spent around 35 minutes...The next task of 26 questions in around 40 minutes can become daunting with 2 RC passage still remaining... N when you are pressed for time in verbal..you tend to lose your comprehension..
Now, this is the point where fellow test takers have gone down...So, I wanna know what is to be done in this scenario...
Btw... I hope you found the passage tough...if you found the passage EASY, then i would rather take a 12th bio book and start studying from that first...
Even if you found this one easy, what would approach be if a tougher passage comes?
