There have been few discussions on this but they are not clear to me..so posting again

While depressed property values can hurt some large investors, they are potentially devastating for homeowners, whose equity - in many cases representing a life's savings - can plunge or even disappear.

(A) they are potentially devastating for homeowners, whose
(B) they can potentially devastate homeowners in that their
(C) for homeowners they are potentially devastating, because their
(D) for homeowners, it is potentially devastating in that their
(E) it can potentially devastate homeowners, whose

OA after some discussion. Please explain options briefly at least.