Sentence Correction

In his research paper, Dr. Frosh, medical director of the Payne Whitney Clinic, distinguishes mood swings. which may be violent without their being grounded in mental disease, from genuine manic-depressive psychosis.

(A) mood swings, which may be violent without their being grounded in mental disease, from genuine manic-depressive psychosis
(B) mood swings, perhaps violent without being grounded in mental disease, and genuine manic-depressive psychosis ,
(C) between mood swings, which may be violent without being grounded in mental disease, and genuine manic-depressive psychosis
(D) between mood swings, perhaps violent without being grounded in mental disease, from genuine manic-depressive psychosis
(E) genuine manic-depressive psychosis and mood swings, which may be violent without being grounded in mental disease

I have question about D.

If i used "and" instead of "from" in D, will it be correct?

What is the difference between "Mood swings, perhaps violent without being grounded in mental disease" and "mood swings, which may be violent without being grounded in mental disease"?

Thanks.