4C2 means that out of 4 possible positions, we want to find out how many ways we can select groups of 2 (order doesn't matter).
In the context of this question, we basically want to find out how many ways we can select groups of 2 digits (order doesn't matter) from a single group of 4 digits.
The formula for combinations is:
n! / k!(n - k)!
When we substitute the values for n and k in the formula we get:
4! / 2!(4 - 2)!
This can be simplified to (4 x 3) / (2 x 1) = 6
Now we need to visualise how those combinations can be arranged:
1. 33XX
2. 3X3X
3. 3XX3
4. X33X
5. X3X3
6. XX33
In 1, 2 and 3: X can be any value from 0 to 9, except for 3.
In 4, 5 and 6: Take note that the X value in the first digit cannot be 0 or 3. The other X value can be any value from 0 to 9, except for 3.
So for the first combination 33XX:
We can see that there is only 1 possibility in the first and second digits (i.e. a 3 in both), and there are 9 possibilities in the 3rd and 4th digits (i.e. any number from 0-9 excluding 3).
When we multiply this out we get 1 x 1 x 9 x 9 = 81.
If you're confused about multiplying it out, then let's digress for a moment.
--- START OF DIGRESSION ---
If you had 2 six-sided die and rolled them both at the same time, then how many possible outcomes could you have?
We know that there are 6 outcomes for the first dice (1,2,3,4,5,6), and then for every outcome of the first dice, we know that there are another 6 outcomes for the second dice (eg. [1,1], [1,2], [1,3], [1,4], [1,5], [1,6], [2,1],[2,2], etc.).
That gives us 6 x 6 = 36 possible outcomes.
--- END OF DIGRESSION ---
So going back to the original question, we can see that for combination 1 we can have only 1 possibility in the first and second positions, and 9 possibilities in the third and fourth positions.
That means you can have 81 different 4-digit numbers that have 33 as the first two digits, and don't have any remaining 3s in the last two digits.
If we follow this formula for all of the combinations we get:
1. 1 x 1 x 9 x 9 = 81
2. 1 x 9 x 1 x 9 = 81
3. 1 x 9 x 9 x 1 = 81
4. 8 x 1 x 1 x 9 = 72
5. 8 x 1 x 9 x 1 = 72
6. 8 x 9 x 1 x 1 = 72
4, 5, and 6 all have 8 ways for the first digit since 0 and 3 are invalid values.
Add all the possibilities together and you get 459.
Hope that is clear.