Sentence Correction

Some patients who do not respond to therapies for depression may simply have received inadequate treatment, having, for example, been prescribed a drug at a dosage too low to be effective or having been taken off a drug too soon.
(A) having, for example, been prescribed a drug at a dosage too low to be effective or having been
(B) having, for example, a drug prescription that was ineffective because the dosage was too low, or being
(C) as, for example, having too low of a dosage of a prescribed drug for it to be effective, or being
(D) when they have, for example, been prescribed too low a drug dosage for it to be effective, or were
(E) for example, when they have a drug prescription with a dosage too low to be effective, or been

Could you please explain how Option A is correct in this question?