Sentence Correction

The Anasazi settlements at Chaco Canyon were built on a spectacular scale with more than 75 carefully engineered structures, of up to 600 rooms each, were connected by a complex regional system of roads.

(A)
with more than 75 carefully engineered structures, of up to 600 rooms each, were

(B)
with more than 75 carefully engineered structures, of up to 600 rooms each,

(C)
of more than 75 carefully engineered structures of up to 600 rooms, each that had been

(D)
of more than 75 carefully engineered structures of up to 600 rooms and with each

(E)
of more than 75 carefully engineered structures of up to 600 rooms each had been

The OA is B. I would like to have more clarity in using with Vs Of in the below phrase. Is there a difference in saying 'scale of' vs 'scale with'.

Is there a difference in saying "spectacular scale with more than 75 carefully engineered structures" Vs "spectacular scale of more than 75 carefully engineered structures".